Hemophagocytic Lymphohistiocytosis, Familial, 5, with or Without Microvillus Inclusion Disease, also known as fhl5, is related to migraine without aura and migraine with aura. An important gene associated with Hemophagocytic Lymphohistiocytosis, Familial, 5, with or Without Microvillus Inclusion Disease is STXBP2 (Syntaxin Binding Protein 2). Affiliated tissues include nk cells and liver.