Holzgreve Syndrome

Alias:

Holzgreve-Wagner-Rehder Syndrome

Holzgreve Wagner Rehder Syndrome

Cleft Palate-Potter Sequence-Congenital Heart Anomalies-Mesoaxial Polydactyly-Multiple Malformations Syndrome

Favorite

Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Holzgreve Syndrome, also known as holzgreve-wagner-rehder syndrome, is related to cleft palate, isolated and polydactyly, postaxial, type a1. An important gene associated with Holzgreve Syndrome is GLI3 (GLI Family Zinc Finger 3), and among its related pathways/superpathways are Focal adhesion and Non-integrin membrane-ECM interactions. Affiliated tissues include heart and tongue, and related phenotypes are cleft palate and intrauterine growth retardation

Related ID：

MALACARDS：HLZ001

OMIM：236110

MESH：C535327