Holoprosencephaly, Recurrent Infections, and Monocytosis is related to holoprosencephaly 1 and holoprosencephaly. An important gene associated with Holoprosencephaly, Recurrent Infections, and Monocytosis is GLI2 (GLI Family Zinc Finger 2), and among its related pathways/superpathways are Signaling by Hedgehog and Wnt / Hedgehog / Notch. Affiliated tissues include monocytes and skin, and related phenotypes are digestive/alimentary and craniofacial