Hellp Syndrome

Hellp Syndrome, also known as hemolysis, elevated liver enzymes, low platelets in pregnancy, is related to eclampsia and pre-eclampsia. An important gene associated with Hellp Syndrome is HELLPAR (HELLP Associated Long Non-Coding RNA), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs Ibuprofen and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include liver and kidney, and related phenotypes are elevated hepatic transaminase and thrombocytopenia