High Pressure Neurological Syndrome is related to tremor and myoclonus, and has symptoms including hyperexplexia An important gene associated with High Pressure Neurological Syndrome is GRIN2A (Glutamate Ionotropic Receptor NMDA Type Subunit 2A), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and CREB Pathway. Affiliated tissues include globus pallidus and brain, and related phenotypes are Decreased caspase 3/7 activity and Reduced mammosphere formation