Hfe Hemochromatosis, also known as hfe-associated hemochromatosis, is related to hemochromatosis, type 1 and iron metabolism disease. An important gene associated with Hfe Hemochromatosis is HFE (Homeostatic Iron Regulator), and among its related pathways/superpathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and Insulin receptor recycling. The drug Iron has been mentioned in the context of this disorder. Affiliated tissues include liver and bone.