Headache

Headache, also known as headache disorder, is related to migraine without aura and cluster headache. An important gene associated with Headache is BRCA2 (BRCA2 DNA Repair Associated), and among its related pathways/superpathways are Nuclear receptors meta-pathway and Development Ligand-independent activation of ESR1 and ESR2. The drugs Fosaprepitant and Aprepitant have been mentioned in the context of this disorder. Affiliated tissues include eye and pituitary, and related phenotypes are nervous system and homeostasis/metabolism