Gynecomastia

Gynecomastia is related to 17-beta hydroxysteroid dehydrogenase iii deficiency and 46,xx sex reversal 1. An important gene associated with Gynecomastia is CYP19A1 (Cytochrome P450 Family 19 Subfamily A Member 1), and among its related pathways/superpathways are Signal Transduction and Metabolism of steroids. The drugs Tamoxifen and (R)-Bicalutamide have been mentioned in the context of this disorder. Affiliated tissues include breast and prostate, and related phenotypes are homeostasis/metabolism and growth/size/body region