Gastritis, Familial Giant Hypertrophic, also known as menetrier disease, is related to protein-losing enteropathy and lymphocytic gastritis, and has symptoms including dyspepsia An important gene associated with Gastritis, Familial Giant Hypertrophic is TGFA (Transforming Growth Factor Alpha), and among its related pathways/superpathways is Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs Cetuximab and Antineoplastic Agents, Immunological have been mentioned in the context of this disorder. Affiliated tissues include colon and pancreas, and related phenotypes are giant hypertrophic gastritis and abnormal gastric mucosa morphology