Gray Zone Lymphoma, also known as b-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical hodgkin lymphoma, is related to mediastinal gray zone lymphoma and lymphoma, hodgkin, classic. An important gene associated with Gray Zone Lymphoma is TNFRSF8 (TNF Receptor Superfamily Member 8), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. The drugs Temsirolimus and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include t cells and bone marrow, and related phenotypes are Increased shRNA abundance (Z-score > 2) and homeostasis/metabolism