Graves Disease 1 (GRD1)

Alias:
Thyrotoxicosis
Graves Disease, Susceptibility to, 1
Uninodular Toxic Struma with Hyperthyroidism
Toxic Uninodular Goitre with Hyperthyroidism
Thyrotoxicosis Due to Single Thyroid Nodule
Thyrotoxicosis with Toxic Uninodular Goitre
Multinodular Goitre with Hyperthyroidism
Thyrotoxicosis Due to Uninodular Goitre
Multinodular Goitre with Thyrotoxicosis
Adenomatous Goitre with Hyperthyroidism
Toxic Diffuse Goitre with Exophthalmos
Uninodular Goitre in Hyperthyroidism
Hyperthyroidism with Thyroid Nodule
Uninodular Goitre in Thyrotoxicosis
Nodular Goitre with Hyperthyroidism
Nodular Struma with Hyperthyroidism
Nodular Goitre with Thyrotoxicosis
Toxic Primary Thyroid Hyperplasia
Thyrotoxicosis Adenomatous Goitre
Thyrotoxicosis Adenomatous Struma
Graves Disease with Exophthalmos
Thyrotoxicosis Nodular Goitre
Hyperthyroidism, Autoimmune
Goitre with Hyperthyroidism
Thyrotoxicosis with Goitre
Hyperactive Thyroid Gland
Toxic Multinodular Goitre
Toxic Adenomatous Goitre
Toxic Adenomatous Struma
Toxic Nodular Goitre Nos
Toxic Uninodular Goitre
Uninodular Toxic Struma
Hyperthyroidism Struma
Malignant Exophthalmos
Thyrotoxicosis Struma
Toxic Diffuse Goitre
Thyroid Exophthalmos
Toxic Thyroid Nodule
Toxic Nodular Struma
Exophthalmic Goitre
Exophthalmic Struma
Hyperthyroid Goitre
Toxic Struma Nodosa
Overactive Thyroid
Toxic Goitre Nos
Plummer Disease
Hyperthyroidism
Basedow Disease
Flajani Disease
Graves Disease
Stokes Disease
Parry Disease
Toxic Goitre
Grd1
Grd
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Graves Disease 1, also known as thyrotoxicosis, is related to neonatal thyrotoxicosis and thyrotoxic exophthalmos. An important gene associated with Graves Disease 1 is GRD1 (Graves Disease, Susceptiblity To, 1), and among its related pathways/superpathways are Thyroid hormones production and peripheral downstream signaling effects and Development_Leptin signaling via JAK/STAT and MAPK cascades. The drugs Parathyroid hormone and Iodine have been mentioned in the context of this disorder. Affiliated tissues include thyroid and heart, and related phenotypes are homeostasis/metabolism and growth/size/body region
Related ID:
MESH:D013971
ICD11:1328823989

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AR
AD
Unknown
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22
235
38

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

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CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
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IF
No Data Found!
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