Granulomatosis with Polyangiitis (GPA)

Granulomatosis with Polyangiitis, also known as gpa, is related to churg-strauss syndrome and polyarteritis nodosa. An important gene associated with Granulomatosis with Polyangiitis is PRTN3 (Proteinase 3), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Alemtuzumab and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include skin and neutrophil, and related phenotypes are recurrent respiratory infections and fatigue