Genetic Atypical Hemolytic-Uremic Syndrome, also known as familial atypical hemolytic-uremic syndrome, is related to thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome. An important gene associated with Genetic Atypical Hemolytic-Uremic Syndrome is CD46 (CD46 Molecule), and among its related pathways/superpathways are Complement cascade and Diseases of hemostasis. Affiliated tissues include kidney and pancreatic islet.