Generalized Epilepsy with Febrile Seizures Plus, Type 4 (GEFSP4)

Generalized Epilepsy with Febrile Seizures Plus, Type 4, also known as generalized epilepsy with febrile seizures plus 4, is related to developmental and epileptic encephalopathy 43 and juvenile absence epilepsy. An important gene associated with Generalized Epilepsy with Febrile Seizures Plus, Type 4 is GEFSP4 (Epilepsy, Generalized, With Febrile Seizures Plus, Type 4), and among its related pathways/superpathways are mBDNF and proBDNF regulation of GABA neurotransmission and Synaptic Neurotransmission: GABAergic Inhibition. Related phenotypes are bilateral tonic-clonic seizure and febrile seizure (within the age range of 3 months to 6 years)