Gingivitis, also known as chronic gingivitis, is related to necrotizing ulcerative gingivitis and periodontitis, chronic, and has symptoms including signs and symptoms, digestive, tenderness of gums and denture irritation. An important gene associated with Gingivitis is MMP8 (Matrix Metallopeptidase 8), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Hexetidine and Metronidazole have been mentioned in the context of this disorder. Affiliated tissues include ovary and endothelial, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and neoplasm