Gingival Overgrowth

Alias:
Gingival Enlargement
Gingival Hyperplasia
Hypertrophy of Mucous Membrane of Gums
Gingival Enlargement Nos
Hyperplasia of Gingiva
Hypertrophy of Gingiva
Gingival Hypertrophy
Gingival Thickening
Gum Hypertrophy
Hyperplasia Gum
Gingival Bulge
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Gingival Overgrowth, also known as gingival enlargement, is related to facial dysmorphism, hypertrichosis, epilepsy, intellectual/developmental delay, and gingival overgrowth syndrome and gingival fibromatosis. An important gene associated with Gingival Overgrowth is KCNK4 (Potassium Two Pore Domain Channel Subfamily K Member 4), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Phenytoin and Folic acid have been mentioned in the context of this disorder. Affiliated tissues include kidney and heart, and related phenotypes are Increased shRNA abundance (Z-score > 2) and homeostasis/metabolism
Related ID:
MESH:D019214
ICD11:1517220932

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Unknown
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41
607
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Medical Symptom

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Description
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Gene & Mutation

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Disease Model

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MGI
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References Literature

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