Glycine Encephalopathy (NKA)

Glycine Encephalopathy, also known as non-ketotic hyperglycinemia, is related to glycine encephalopathy 1 and glycine encephalopathy 2, and has symptoms including lethargy, myoclonus and seizures. An important gene associated with Glycine Encephalopathy is AMT (Aminomethyltransferase), and among its related pathways/superpathways are Regulation of expression of SLITs and ROBOs and Mitochondrial iron-sulfur cluster biogenesis. Affiliated tissues include brain and cortex, and related phenotypes are seizure and eeg abnormality