Glutamate-Cysteine Ligase Deficiency

Glutamate-Cysteine Ligase Deficiency, also known as gamma-glutamylcysteine synthetase deficiency, is related to deficiency anemia and hemolytic anemia. An important gene associated with Glutamate-Cysteine Ligase Deficiency is GCLC (Glutamate-Cysteine Ligase Catalytic Subunit), and among its related pathways/superpathways are Glutathione conjugation and One-carbon metabolism and related pathways. Affiliated tissues include cortex, and related phenotypes are hemolytic anemia and myopathy