Glucosephosphate Isomerase Deficiency, also known as glucose phosphate isomerase deficiency, is related to hemolytic anemia and hemolytic anemia, nonspherocytic, due to glucose phosphate isomerase deficiency, and has symptoms including absence seizures An important gene associated with Glucosephosphate Isomerase Deficiency is PIGM (Phosphatidylinositol Glycan Anchor Biosynthesis Class M). Affiliated tissues include spleen and skin.