Glucose Intolerance, also known as impaired glucose tolerance, is related to lipodystrophy, familial partial, type 2 and abdominal obesity-metabolic syndrome 1. An important gene associated with Glucose Intolerance is MT-TL1 (Mitochondrially Encoded TRNA-Leu (UUA/G) 1), and among its related pathways/superpathways are Signal Transduction and PI3K-Akt signaling pathway. The drugs Orlistat and Nateglinide have been mentioned in the context of this disorder. Affiliated tissues include pancreatic islet and skeletal muscle, and related phenotypes are homeostasis/metabolism and adipose tissue