Goodpasture Syndrome

Goodpasture Syndrome, also known as anti-glomerular basement membrane disease, is related to anti-basement membrane glomerulonephritis and hemosiderosis. An important gene associated with Goodpasture Syndrome is COL4A3 (Collagen Type IV Alpha 3 Chain), and among its related pathways/superpathways are Innate Immune System and Phospholipase-C Pathway. The drugs Cyclophosphamide and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include kidney and lung, and related phenotypes are respiratory insufficiency and proteinuria