Fetal Encasement Syndrome (COCOS)

Fetal Encasement Syndrome, also known as cocoon syndrome, is related to intestinal obstruction and peritonitis, and has symptoms including morning sickness An important gene associated with Fetal Encasement Syndrome is CHUK (Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex), and among its related pathways/superpathways are TNFR1 Pathway and 4-1BB Pathway. The drugs Levetiracetam and Nootropic Agents have been mentioned in the context of this disorder. Affiliated tissues include skin and lung, and related phenotypes are decreased fetal movement and omphalocele