Fatal Familial Insomnia (FFI)

Fatal Familial Insomnia, also known as insomnia, fatal familial, is related to frontotemporal lobar degeneration with tdp43 inclusions, grn-related and sleep disorder, and has symptoms including apnea, ataxia and constipation. An important gene associated with Fatal Familial Insomnia is PRNP (Prion Protein (Kanno Blood Group)), and among its related pathways/superpathways are Alzheimer's disease and miRNA effects and Neuroscience. The drugs Doxycycline and Anti-Bacterial Agents have been mentioned in the context of this disorder. Affiliated tissues include thalamus and brain, and related phenotypes are myoclonus and ataxia