Fissured Tongue, also known as furrowed tongue, is related to melkersson-rosenthal syndrome and arthrogryposis, distal, type 5d, and has symptoms including glossalgia An important gene associated with Fissured Tongue is NSD2 (Nuclear Receptor Binding SET Domain Protein 2), and among its related pathways/superpathways are Cardiac conduction and Striated muscle contraction pathway. Affiliated tissues include tongue and liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and cardiovascular system