Fish-Eye Disease (FED)

Fish-Eye Disease, also known as fed, is related to lecithin:cholesterol acyltransferase deficiency and hypoalphalipoproteinemia, primary, 2. An important gene associated with Fish-Eye Disease is LCAT (Lecithin-Cholesterol Acyltransferase), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Plasma lipoprotein assembly, remodeling, and clearance. The drugs Hydrocortisone and Hydrocortisone acetate have been mentioned in the context of this disorder. Affiliated tissues include eye and heart, and related phenotypes are corneal opacity and decreased hdl cholesterol concentration