Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 (FTDALS7)

Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7, also known as chromosome 3-linked frontotemporal dementia, is related to toxic encephalopathy and tauopathy, and has symptoms including muscle rigidity, myoclonus and abnormal pyramidal signs. An important gene associated with Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 is CHMP2B (Charged Multivesicular Body Protein 2B), and among its related pathways/superpathways are Infectious disease and Vesicle-mediated transport. Affiliated tissues include spinal cord and temporal lobe, and related phenotypes are nervous system and mortality/aging