Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 4 (FTDALS4)

Alias:
Ftdals4
Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis-4
Dementia, Frontotemporal, and/or Amyotrophic Lateral Sclerosis, Type 4
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 4, also known as ftdals4, is related to amyotrophic lateral sclerosis 21 and spondylometaphyseal dysplasia, axial. An important gene associated with Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 4 is TBK1 (TANK Binding Kinase 1), and among its related pathways/superpathways are NF-kB (NFkB) Pathway and SARS-CoV-2 innate immunity evasion and cell-specific immune response. Affiliated tissues include temporal lobe and spinal cord, and related phenotypes are hyperreflexia and dysarthria
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Unknown
--
10
95
20

Medical Symptom

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Description
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No data available

Gene & Mutation

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Related Drugs

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No data available

Disease Model

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MGI
Related Gene
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Publications
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References Literature

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