Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1, also known as amyotrophic lateral sclerosis and/or frontotemporal dementia, is related to frontotemporal dementia and/or amyotrophic lateral sclerosis 2 and frontotemporal dementia and/or amyotrophic lateral sclerosis 3, and has symptoms including muscle weakness, paraparesis and abnormality of extrapyramidal motor function. An important gene associated with Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1 is C9orf72 (C9orf72-SMCR8 Complex Subunit), and among its related pathways/superpathways are Neuroscience and Involvement of -secretase in neurodegenerative diseases. The drugs Dopamine and Memantine have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe and brain, and related phenotypes are abnormal upper motor neuron morphology and frontotemporal dementia