Frontotemporal Dementia (FTD)

Alias:
Frontotemporal Lobar Degeneration
Pallidopontonigral Degeneration
Dementia, Frontotemporal
Ftd
Multiple System Tauopathy with Presenile Dementia
Frontotemporal Lobe Dementia
Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex
Frontotemporal Lobar Degeneration with Tau Inclusions
Frontotemporal Dementia with Parkinsonism
Ftld with Tau Inclusions
Wilhelmsen-Lynch Disease
Ftdp17
Fldem
Ddpac
Mstd
Ppnd
Wld
Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17
Dementia, Frontotemporal, with or Without Parkinsonism
Frontotemporal Dementia-Amyotrophic Lateral Sclerosis
Frontotemporal Dementia with Motor Neuron Disease
Dementia in Fronto-Temporal Lobar Degeneration
Frontotemporal Dementia with Parkinsonism-17
Dementia, Frontotemporal, with Parkinsonism
Grn-Related Frontotemporal Dementia
Ftd - [frontotemporal Dementia]
Pick Disease of the Brain
Wilhemsen-Lynch Disease
Frontal Lobe Dementia
Temple Dementia
Pick Complex
Ftd-Als
Ftld
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Frontotemporal Dementia, also known as frontotemporal lobar degeneration, is related to frontotemporal dementia and/or amyotrophic lateral sclerosis 1 and frontotemporal dementia and/or amyotrophic lateral sclerosis 7, and has symptoms including myoclonus and personality changes. An important gene associated with Frontotemporal Dementia is MAPT (Microtubule Associated Protein Tau), and among its related pathways/superpathways are Innate Immune System and Neuroscience. The drugs Miglustat and Memantine have been mentioned in the context of this disorder. Affiliated tissues include brain and amygdala, and related phenotypes are amyotrophic lateral sclerosis and dementia
Related ID:
MESH:C563003
ICD11:2099230583

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Adult
1-9/100000
127
1436
334

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

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CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
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IF
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