Fragile Site, Distamycin a Type, Rare, Fra(16)(q22.1), also known as fragile site 16q22, is related to fragile site 10q25 and fragile x syndrome. An important gene associated with Fragile Site, Distamycin a Type, Rare, Fra(16)(q22.1) is FRA16B (Fragile Site, Distamycin A Type, Rare, Fra(16)(Q22.1)). Affiliated tissues include lymph node and bone marrow, and related phenotypes are infertility and abnormality of chromosome segregation