Familial Hypofibrinogenemia, also known as hypofibrinogenemia, familial, is related to afibrinogenemia, congenital and alpha-1-antitrypsin deficiency. An important gene associated with Familial Hypofibrinogenemia is FGA (Fibrinogen Alpha Chain), and among its related pathways/superpathways are MyD88 dependent cascade initiated on endosome and Class I MHC mediated antigen processing and presentation. Affiliated tissues include liver, and related phenotypes are gastrointestinal hemorrhage and epistaxis