Familial Afibrinogenemia is related to afibrinogenemia, congenital and pulmonary embolism. An important gene associated with Familial Afibrinogenemia is FGA (Fibrinogen Alpha Chain), and among its related pathways/superpathways are MyD88 dependent cascade initiated on endosome and Class I MHC mediated antigen processing and presentation. Related phenotypes are joint swelling and epistaxis