Familial Pityriasis Rubra Pilaris

Familial Pityriasis Rubra Pilaris, also known as pityriasis rubra pilaris--familial type, is related to pityriasis rubra pilaris and contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a. An important gene associated with Familial Pityriasis Rubra Pilaris is CARD14 (Caspase Recruitment Domain Family Member 14). Affiliated tissues include skin, and related phenotype is Increased shRNA abundance (Z-score > 2).