Familial Adenomatous Polyposis 1, also known as gardner syndrome, is related to apc-associated polyposis conditions and desmoid disease, hereditary, and has symptoms including abdominal pain and diarrhea. An important gene associated with Familial Adenomatous Polyposis 1 is APC (APC Regulator Of WNT Signaling Pathway), and among its related pathways/superpathways are Arf6 trafficking events and Presenilin action in Notch and Wnt signaling. The drugs Azithromycin and Erythromycin have been mentioned in the context of this disorder. Affiliated tissues include colon and thyroid, and related phenotypes are brain neoplasm and neoplasm of the central nervous system