Familial Adenomatous Polyposis 1 (FAP1)

Alias:
Gardner Syndrome
Brain Tumor-Polyposis Syndrome 2
Adenomatous Polyposis Coli
Apc-Related Attenuated Familial Adenomatous Polyposis
Adenomatous Polyposis of the Colon
Familial Polyposis of the Colon
Turcot Syndrome with Polyposis
Fap1
Apc
Fpc
Apc-Related Attenuated Familial Polyposis Coli
Adenomatous Polyposis Coli, Susceptibility to
Adenomatous Polyposis, Familial, Type 1
Familial Multiple Polyposis Syndrome
Polyposis, Adenomatous Intestinal
Adenoma, Periampullary, Somatic
Apc-Related Attenuated Fap
Gardner's Syndrome
Gardners Syndrome
Apc-Related Afap
Favorite
Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Familial Adenomatous Polyposis 1, also known as gardner syndrome, is related to apc-associated polyposis conditions and desmoid disease, hereditary, and has symptoms including abdominal pain and diarrhea. An important gene associated with Familial Adenomatous Polyposis 1 is APC (APC Regulator Of WNT Signaling Pathway), and among its related pathways/superpathways are Arf6 trafficking events and Presenilin action in Notch and Wnt signaling. The drugs Azithromycin and Erythromycin have been mentioned in the context of this disorder. Affiliated tissues include colon and thyroid, and related phenotypes are brain neoplasm and neoplasm of the central nervous system
Related ID:
MESH:D011125
ICD11:1428130769

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AR
AD
Unknown
--
11
157
516

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top