Familial Cold Autoinflammatory Syndrome 4 (FCAS4)

Familial Cold Autoinflammatory Syndrome 4, also known as fcas4, is related to panniculitis and immunodeficiency 31a. An important gene associated with Familial Cold Autoinflammatory Syndrome 4 is NLRC4 (NLR Family CARD Domain Containing 4), and among its related pathways/superpathways are Inflammasomes and Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways. Affiliated tissues include skin and bone, and related phenotypes are fever and arthralgia