Familial Cerebral Saccular Aneurysm, also known as familial intracranial saccular aneurysm, is related to intracranial berry aneurysm and cerebral arterial disease. An important gene associated with Familial Cerebral Saccular Aneurysm is ANGPTL6 (Angiopoietin Like 6), and among its related pathways/superpathways are Phospholipase-C Pathway and Wnt / Hedgehog / Notch. Affiliated tissues include endothelial and brain, and related phenotypes are cerebral berry aneurysm and seizure