Familial Cold Autoinflammatory Syndrome 2 (FCAS2)

Familial Cold Autoinflammatory Syndrome 2, also known as fcas2, is related to familial cold autoinflammatory syndrome 1 and familial cold autoinflammatory syndrome. An important gene associated with Familial Cold Autoinflammatory Syndrome 2 is NLRP12 (NLR Family Pyrin Domain Containing 12), and among its related pathways/superpathways are Nucleotide-binding oligomerization domain (NOD) pathway and Deregulation of Rab and Rab effector genes in bladder cancer. Affiliated tissues include skin and bone, and related phenotypes are elevated circulating c-reactive protein concentration and elevated erythrocyte sedimentation rate