Familial Cold Autoinflammatory Syndrome 1 (FCAS1)

Familial Cold Autoinflammatory Syndrome 1, also known as familial cold urticaria, is related to cryopyrin-associated periodic syndrome and familial cold autoinflammatory syndrome 2. An important gene associated with Familial Cold Autoinflammatory Syndrome 1 is NLRP3 (NLR Family Pyrin Domain Containing 3), and among its related pathways/superpathways are Innate Immune System and TNF Superfamily - Human Ligand-Receptor Interactions and their Associated Functions. The drugs Ginseng and Calcium polycarbophil have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are hyperhidrosis and arthritis