Familial Thoracic Aortic Aneurysm and Dissection (FAA)

Familial Thoracic Aortic Aneurysm and Dissection, also known as congenital aneurysm of ascending aorta, is related to aortic aneurysm, familial thoracic 10 and loeys-dietz syndrome 1. An important gene associated with Familial Thoracic Aortic Aneurysm and Dissection is SMAD3 (SMAD Family Member 3), and among its related pathways/superpathways are Extracellular matrix organization and Burn wound healing. The drugs Acetazolamide and Iodine have been mentioned in the context of this disorder. Affiliated tissues include heart and skin, and related phenotypes are renal/urinary system and muscle