Familial Hypercholesterolemia (FH)

Familial Hypercholesterolemia, also known as hyperlipoproteinemia type iia, is related to homozygous familial hypercholesterolemia and hyperlipoproteinemia, type iii. An important gene associated with Familial Hypercholesterolemia is LDLR (Low Density Lipoprotein Receptor), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Metabolism of water-soluble vitamins and cofactors. The drugs Clotrimazole and Heparin, bovine have been mentioned in the context of this disorder. Affiliated tissues include Liver and heart, and related phenotypes are Increased free cholesterol and liver/biliary system