Familial Retinoblastoma

Familial Retinoblastoma, also known as hereditary retinoblastoma, is related to intraocular retinoblastoma and blastoma. An important gene associated with Familial Retinoblastoma is RB1 (RB Transcriptional Corepressor 1), and among its related pathways/superpathways are Infectious disease and Cell Cycle, Mitotic. The drugs Sargramostim and Nicotine have been mentioned in the context of this disorder. Affiliated tissues include eye and retina, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and neoplasm