Focal Palmoplantar Keratoderma

Focal Palmoplantar Keratoderma, also known as focal palmoplantar hyperkeratosis, is related to palmoplantar keratoderma, nonepidermolytic, focal or diffuse and palmoplantar keratosis. An important gene associated with Focal Palmoplantar Keratoderma is KRT6C (Keratin 6C), and among its related pathways/superpathways are Nervous system development and COPI-independent Golgi-to-ER retrograde traffic. Affiliated tissues include skin and tongue, and related phenotypes are Increased shRNA abundance (Z-score > 2) and digestive/alimentary