Fibrolamellar Carcinoma (FHCC)

Fibrolamellar Carcinoma, also known as fibrolamellar hepatocellular carcinoma, is related to mixed fibrolamellar hepatocellular carcinoma and cholangiocarcinoma, and has symptoms including abdominal pain, fever and icterus. An important gene associated with Fibrolamellar Carcinoma is DNAJB1 (DnaJ Heat Shock Protein Family (Hsp40) Member B1), and among its related pathways/superpathways are Infectious disease and Metabolism. The drugs Sorafenib and Picropodophyllin have been mentioned in the context of this disorder. Affiliated tissues include liver and bone marrow, and related phenotypes are Decreased viability and Increased cell migration