Fibular Aplasia or Hypoplasia, Femoral Bowing and Poly-, Syn-, and Oligodactyly (FUHRS)

Fibular Aplasia or Hypoplasia, Femoral Bowing and Poly-, Syn-, and Oligodactyly, also known as fuhrmann syndrome, is related to ulna and fibula, absence of, with severe limb deficiency and split hand-foot malformation. An important gene associated with Fibular Aplasia or Hypoplasia, Femoral Bowing and Poly-, Syn-, and Oligodactyly is WNT7A (Wnt Family Member 7A), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. Affiliated tissues include bone and uterus, and related phenotypes are hypoplasia of the radius and aplasia/hypoplasia of the ulna