Estrogen Excess, also known as hyperestrogenism, is related to leydig cell tumor and testicular germ cell cancer. An important gene associated with Estrogen Excess is CYP19A1 (Cytochrome P450 Family 19 Subfamily A Member 1), and among its related pathways/superpathways are Signal Transduction and Breast cancer pathway. The drugs Iron and Contraceptive Agents have been mentioned in the context of this disorder. Affiliated tissues include bone and ovary, and related phenotypes are homeostasis/metabolism and neoplasm