Esophageal Disease, also known as esophageal disorder, is related to barrett esophagus and gastroesophageal reflux, and has symptoms including abdominal pain, constipation and coughing. An important gene associated with Esophageal Disease is CEACAM5 (CEA Cell Adhesion Molecule 5), and among its related pathways/superpathways are miRNA role in immune response in sepsis and Cell differentiation - expanded index. The drugs Dopamine and Naloxone have been mentioned in the context of this disorder. Affiliated tissues include lung and heart.