Eosinophilic Fasciitis, also known as diffuse fasciitis with eosinophilia, is related to fasciitis and hypereosinophilic syndrome. An important gene associated with Eosinophilic Fasciitis is IL5 (Interleukin 5). The drugs Rituximab and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are fatigue and acrocyanosis