Eisenmenger Syndrome

Eisenmenger Syndrome, also known as eisenmenger complex, is related to atrial heart septal defect and pulmonary hypertension. An important gene associated with Eisenmenger Syndrome is THBD (Thrombomodulin), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Diseases of hemostasis. The drugs Bosentan and Endothelin Receptor Antagonists have been mentioned in the context of this disorder. Affiliated tissues include heart and skin, and related phenotypes are pulmonary arterial hypertension and abnormal heart morphology