Erythema Nodosum

Erythema Nodosum is related to pulmonary sarcoidosis and ileocolitis. An important gene associated with Erythema Nodosum is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Apremilast and Thalidomide have been mentioned in the context of this disorder. Affiliated tissues include skin and t cells, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Increased shRNA abundance (Z-score > 2)