Erythermalgia, Primary (PERYTHM)

Erythermalgia, Primary, also known as small fiber neuropathy, is related to sodium channelopathy-related small fiber neuropathy and neuropathy, and has symptoms including constipation, diarrhea and pruritus. An important gene associated with Erythermalgia, Primary is SCN9A (Sodium Voltage-Gated Channel Alpha Subunit 9), and among its related pathways/superpathways are Cardiac conduction and Neuropathic Pain-Signaling in Dorsal Horn Neurons. The drugs Antibodies, Blocking and Lacosamide have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and skin, and related phenotypes are peripheral neuropathy and erythema